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Page 1
The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation.
Kim EE, Shekhar A, Ramachandran J, Khodadadi-Jamayran A, Liu FY, Zhang J, Fishman GI. Kim EE, et al. Development. 2023 Nov 1;150(21):dev202054. doi: 10.1242/dev.202054. Epub 2023 Oct 24. Development. 2023. PMID: 37787076 Free PMC article.
Growth abnormalities in Ebf1 knockout hearts are observed as early as embryonic day 13.5. ...Finally, we demonstrate that BMP signaling induces Ebf1 expression in embryonic heart cultures and controls a gene program enriched in EBF1 targets. ...
Growth abnormalities in Ebf1 knockout hearts are observed as early as embryonic day 13.5. ...Finally, we demonstrate that BMP …
EBF1 is expressed in pericytes and contributes to pericyte cell commitment.
Pagani F, Tratta E, Dell'Era P, Cominelli M, Poliani PL. Pagani F, et al. Histochem Cell Biol. 2021 Oct;156(4):333-347. doi: 10.1007/s00418-021-02015-7. Epub 2021 Jul 16. Histochem Cell Biol. 2021. PMID: 34272603 Free PMC article.
Early B-cell factor-1 (EBF1) is a transcription factor with an important role in cell lineage specification and commitment during the early stage of cell maturation. ...In vessels, EBF1 expression and function have never been documented. Our data indicate that EB …
Early B-cell factor-1 (EBF1) is a transcription factor with an important role in cell lineage specification and commitment during the …
The temporal transcriptomic signature of cartilage formation.
Takács R, Vágó J, Póliska S, Pushparaj PN, Ducza L, Kovács P, Jin EJ, Barrett-Jolley R, Zákány R, Matta C. Takács R, et al. Nucleic Acids Res. 2023 May 8;51(8):3590-3617. doi: 10.1093/nar/gkad210. Nucleic Acids Res. 2023. PMID: 36987858 Free PMC article.
Using RNA sequencing, we examined differences in gene expression patterns during cartilage formation in micromass cultures of embryonic limb bud-derived progenitors. Principal component and trajectory analyses revealed a progressively different and distinct transcriptome d …
Using RNA sequencing, we examined differences in gene expression patterns during cartilage formation in micromass cultures of embryonic …
Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages.
Kiviranta R, Yamana K, Saito H, Ho DK, Laine J, Tarkkonen K, Nieminen-Pihala V, Hesse E, Correa D, Määttä J, Tessarollo L, Rosen ED, Horne WC, Jenkins NA, Copeland NG, Warming S, Baron R. Kiviranta R, et al. J Exp Med. 2013 May 6;210(5):969-85. doi: 10.1084/jem.20121187. Epub 2013 Apr 8. J Exp Med. 2013. PMID: 23569325 Free PMC article.
In adult mice, the effects of Zfp521 were largely caused by repression of Ebf1, and the bone phenotype of Zfp521(+/-) mice was rescued in Zfp521(+/-):Ebf1(+/-) mice. Zfp521 interacted with Ebf1 and repressed its transcriptional activity. Accordingly, deletion …
In adult mice, the effects of Zfp521 were largely caused by repression of Ebf1, and the bone phenotype of Zfp521(+/-) mice was rescue …
The role of chick Ebf genes in the mediolateral patterning of the somites.
El-Magd MA, Elsayed SA, El-Shetry ES, Abdelfattah-Hassan A, Saleh AA, Allen S, McGonnell I, Patel K. El-Magd MA, et al. Genesis. 2019 Nov;57(11-12):e23339. doi: 10.1002/dvg.23339. Epub 2019 Nov 13. Genesis. 2019. PMID: 31724301
To determine whether Ebf1 plays a role in somite patterning, transfection of a dominant-negative construct was carried out; this showed suppression of cPax1 expression in the medial sclerotome and upregulation and medial expansion of cEbf3 and cPax3 expression in sclerotom …
To determine whether Ebf1 plays a role in somite patterning, transfection of a dominant-negative construct was carried out; this show …
Shh regulates chick Ebf1 gene expression in somite development.
El-Magd MA, Allen S, McGonnell I, Mansour AA, Otto A, Patel K. El-Magd MA, et al. Gene. 2015 Jan 1;554(1):87-95. doi: 10.1016/j.gene.2014.10.028. Epub 2014 Oct 23. Gene. 2015. PMID: 25455103
To assess this hypothesis, the expression profile of cEbf1 was first detailed in somites of chick embryos (from HH8 to HH28). cEbf1 expression was mainly localised in the medial sclerotome and later around the vertebral cartilage anlagen of body and pedicles. Tissue manipu …
To assess this hypothesis, the expression profile of cEbf1 was first detailed in somites of chick embryos (from HH8 to HH28). cEbf1 expressi …
The effect of RA on the chick Ebf1-3 genes expression in somites and pharyngeal arches.
El-Magd MA, Saleh AA, El-Aziz RM, Salama MF. El-Magd MA, et al. Dev Genes Evol. 2014 Dec;224(4-6):245-53. doi: 10.1007/s00427-014-0483-y. Epub 2014 Oct 21. Dev Genes Evol. 2014. PMID: 25331756
Expression of chick early B cell factor 1-3 (cEbf1-3) genes in regions of high retinoic acid (RA) activity, such as somites and pharyngeal arches (PAs), and regulation of other EBF members by RA raise the possibility that the internal cue RA may regulate cEbf1-3 expression in the …
Expression of chick early B cell factor 1-3 (cEbf1-3) genes in regions of high retinoic acid (RA) activity, such as somites and pharyngeal a …
Regulation of early adipose commitment by Zfp521.
Kang S, Akerblad P, Kiviranta R, Gupta RK, Kajimura S, Griffin MJ, Min J, Baron R, Rosen ED. Kang S, et al. PLoS Biol. 2012;10(11):e1001433. doi: 10.1371/journal.pbio.1001433. Epub 2012 Nov 27. PLoS Biol. 2012. PMID: 23209378 Free PMC article.
In addition, Zfp521-/- embryos exhibit increased mass of interscapular brown adipose tissue and subcutaneous white adipocytes, a cell autonomous effect. Finally, Ebf1 participates in a negative feedback loop to repress Zfp521 as differentiation proceeds. ...
In addition, Zfp521-/- embryos exhibit increased mass of interscapular brown adipose tissue and subcutaneous white adipocytes, a cell …
Genoarchitectonic profile of developing nuclear groups in the chicken pretectum.
Ferran JL, de Oliveira ED, Merchán P, Sandoval JE, Sánchez-Arrones L, Martínez-De-La-Torre M, Puelles L. Ferran JL, et al. J Comp Neurol. 2009 Dec 1;517(4):405-51. doi: 10.1002/cne.22115. J Comp Neurol. 2009. PMID: 19790262
Transcription-factor gene markers were used to selectively map derivatives of the three pretectal histogenetic domains: Pax7 and Pax6 (CoP); FoxP1 and Six3 (JcP); and FoxP2, Ebf1, and Bhlhb4 (PcP). The combination of this genoarchitectonic information with additional data …
Transcription-factor gene markers were used to selectively map derivatives of the three pretectal histogenetic domains: Pax7 and Pax6 (CoP); …
29 results